Mammalian septins nomenclature. Academic Article uri icon

Overview

MeSH

  • Alternative Splicing
  • Animals
  • Cytoskeletal Proteins
  • Fungal Proteins
  • GTP-Binding Proteins
  • Humans
  • Phylogeny
  • Protein Structure, Tertiary
  • Septins

MeSH Major

  • GTP Phosphohydrolases
  • Terminology as Topic

abstract

  • There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct names given to splice variants of the same gene. Moreover, some names are based on those of yeast or Drosophila septins that are not the closest homologues. Therefore, we suggest that the mammalian septin field adopt a common nomenclature system, based on that adopted by the Mouse Genomic Nomenclature Committee and accepted by the Human Genome Organization Gene Nomenclature Committee. The human and mouse septin genes will be named SEPT1-SEPT10 and Sept1-Sept10, respectively. Splice variants will be designated by an underscore followed by a lowercase "v" and a number, e.g., SEPT4_v1.

publication date

  • December 2002

has subject area

  • Alternative Splicing
  • Animals
  • Cytoskeletal Proteins
  • Fungal Proteins
  • GTP Phosphohydrolases
  • GTP-Binding Proteins
  • Humans
  • Phylogeny
  • Protein Structure, Tertiary
  • Septins
  • Terminology as Topic

Research

keywords

  • Journal Article

Identity

Language

  • eng

PubMed Central ID

  • PMC138619

Digital Object Identifier (DOI)

  • 10.1091/mbc.E02-07-0438

PubMed ID

  • 12475938

Additional Document Info

start page

  • 4111

end page

  • 4113

volume

  • 13

number

  • 12