Mammalian septins nomenclature Academic Article uri icon


MeSH Major

  • GTP Phosphohydrolases
  • Terminology as Topic


  • There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct names given to splice variants of the same gene. Moreover, some names are based on those of yeast or Drosophila septins that are not the closest homologues. Therefore, we suggest that the mammalian septin field adopt a common nomenclature system, based on that adopted by the Mouse Genomic Nomenclature Committee and accepted by the Human Genome Organization Gene Nomenclature Committee. The human and mouse septin genes will be named SEPT1-SEPT10 and Sept1-Sept10, respectively. Splice variants will be designated by an underscore followed by a lowercase "v" and a number, e.g., SEPT4_v1.

publication date

  • December 2002



  • Academic Article



  • eng

PubMed Central ID

  • PMC138619

Digital Object Identifier (DOI)

  • 10.1091/mbc.E02-07-0438

PubMed ID

  • 12475938

Additional Document Info

start page

  • 4111

end page

  • 3


  • 13


  • 12