Radical resection of rectal cancer primary tumor provides effective local therapy in patients with stage IV disease
Antineoplastic Combined Chemotherapy Protocols
Practice Guidelines as Topic
For patients who present with distant metastases and resectable primary rectal cancers, radical surgery without radiotherapy can provide durable local control with acceptable morbidity. The extent of metastatic disease and the response to chemotherapy are the major determinants of survival. Effective systemic chemotherapy should be given high priority in the treatment of stage IV rectal cancer.