Immunoglobulin A-associated lymphocytic vasculopathy: A clinicopathologic study of eight patients Academic Article Article uri icon

Overview

MeSH Major

  • Lymphoma, T-Cell, Cutaneous
  • Precancerous Conditions
  • Skin Neoplasms

abstract

  • A non-necrotizing lymphocytic purpuric vascular reaction is one manifestation of vascular IgA deposition in the skin. A subpopulation of human lymphocytes bear surface Fc receptor and/or C3 receptors ('complement receptor lymphocytes') which can bind circulating immune complexes (ICs) or C3 generated via activation of the alternative complement cascade. Thus, circulating ICs are a potential pathogenic basis of this eruption, the histologic differential diagnosis of which is idiopathic PP and PP of drug or viral etiology.

publication date

  • November 2002

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1034/j.1600-0560.2002.291005.x

PubMed ID

  • 12453297

Additional Document Info

start page

  • 596

end page

  • 601

volume

  • 29

number

  • 10