In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe Academic Article Article uri icon

Overview

MeSH Major

  • Aortic Valve
  • Atherosclerosis
  • Calcinosis
  • Durapatite
  • Heart Valve Diseases
  • Muscle, Smooth, Vascular
  • Vascular Calcification

abstract

  • Thrombin activity can be imaged in vivo by using a novel thrombin-activatable and thrombin-specific NIR molecular probe. The thrombin probe could enhance the understanding of the role of thrombin in thrombogenesis and other homeostatic and pathological conditions.

publication date

  • November 2002

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1161/01.ATV.0000033089.56970.2D

PubMed ID

  • 12426227

Additional Document Info

start page

  • 1929

end page

  • 35

volume

  • 22

number

  • 11