In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe
Heart Valve Diseases
Muscle, Smooth, Vascular
Thrombin activity can be imaged in vivo by using a novel thrombin-activatable and thrombin-specific NIR molecular probe. The thrombin probe could enhance the understanding of the role of thrombin in thrombogenesis and other homeostatic and pathological conditions.