To excise or to sample the mammographic target: what is the goal of stereotactic 11-gauge vacuum-assisted breast biopsy? Academic Article uri icon

Overview

MeSH

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Hyperplasia
  • Middle Aged
  • Retrospective Studies

MeSH Major

  • Biopsy, Needle
  • Breast Neoplasms
  • Carcinoma, Intraductal, Noninfiltrating
  • Mammography
  • Stereotaxic Techniques
  • Vacuum

abstract

  • This study was undertaken to determine whether complete percutaneous excision rather than sampling of the mammographic target conveys any significant advantage or disadvantage at stereotactic 11-gauge vacuum-assisted biopsy. A retrospective review was performed of 788 consecutive solitary lesions in which the mammographic target was excised (n = 466) or sampled (n = 322) at stereotactic 11-gauge vacuum-assisted biopsy. Medical records and histologic findings were reviewed to determine the frequency of sparing surgery, discordance, histologic underestimation, rebiopsy, complete histologic removal of cancer, and complications. Statistical comparisons were made using the Fisher's exact test. Complete excision rather than sampling of the mammographic target was associated with a significantly lower frequency of discordance (1/466, 0.2% vs 8/322, 2.5%; p = 0.004) and a trend toward fewer ductal carcinoma in situ underestimates (4/59, 6.8% vs 12/60, 20.0%; p = 0.07). Complete histologic removal of cancer was significantly more likely if the mammographic target was excised rather than sampled (19/91, 20.9% vs 7/106, 6.6%; p = 0.006); however, among 91 cancers in which the mammographic target was excised, surgery revealed residual cancer in 72 (79.1%). Complete excision rather than sampling of the mammographic target yielded no significant differences in the frequency of sparing surgery, atypical ductal hyperplasia underestimates, rebiopsy, or complications. Complete excision rather than sampling of the mammographic target was associated with lower frequencies of discordance and ductal carcinoma in situ underestimation but had no other advantage or disadvantage. Among cancers in which the mammographic target was excised, surgery revealed residual cancer in almost 80%.

publication date

  • September 2002

has subject area

  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Needle
  • Breast Neoplasms
  • Carcinoma, Intraductal, Noninfiltrating
  • Female
  • Humans
  • Hyperplasia
  • Mammography
  • Middle Aged
  • Retrospective Studies
  • Stereotaxic Techniques
  • Vacuum

Research

keywords

  • Case Reports
  • Journal Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.2214/ajr.179.3.1790679

PubMed ID

  • 12185043

Additional Document Info

start page

  • 679

end page

  • 683

volume

  • 179

number

  • 3