Megakaryocytes mimicking metastatic breast carcinoma: A potential trap in the interpretation of sentinel lymp nodes Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Breast Neoplasms
  • Lymph Nodes
  • Megakaryocytes

abstract

  • False-positive diagnosis of lymph nodes occurs when a benign element in a lymph node, or in its capsule, is interpreted as metastatic carcinoma. This report describes a patient with breast carcinoma who had megakaryocytes in axillary sentinel lymph nodes mimicking metastatic carcinoma. The patient had no history of a hematologic disease, and we found no evidence of a concurrent hematopoietic disorder. The megakaryocytes were reactive for CD31, CD61, and von Willebrand factor, but not for cytokeratin (AE1/AE3). Megakaryocytes should be added to the list of benign histologic abnormalities that may simulate metastatic carcinoma in a sentinel lymph node.

publication date

  • May 18, 2002

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11958674

Additional Document Info

start page

  • 618

end page

  • 20

volume

  • 126

number

  • 5