Salvage chemotherapy for patients with advanced pure seminoma Academic Article Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Urinary Bladder Neoplasms

abstract

  • Most patients with advanced seminoma are cured with standard first-line programs of cisplatin and etoposide with or without bleomycin. A small minority of patients with pure seminoma have resistant tumors and require salvage chemotherapy. In this setting, approximately 50% of patients with recurrent pure seminoma achieve durable CR with conventional or high-dose salvage chemotherapy. Identification of biologic markers to predict clinical outcome and an enhanced understanding of the basic biologic features of seminoma may lead to improvements in the management of this disease.

publication date

  • January 2002

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1200/JCO.20.1.297

PubMed ID

  • 11773182

Additional Document Info

start page

  • 297

end page

  • 301

volume

  • 20

number

  • 1