Pneumocystis carinii pneumonia in patients with diamond-blackfan anemia receiving high-dose corticosteroids Academic Article Article uri icon

Overview

MeSH Major

  • Chelation Therapy
  • Iron Chelating Agents
  • Iron Overload

abstract

  • The authors describe three infants with Diamond-Blackfan anemia receiving corticosteroids who were diagnosed with Pneumocystis carinii pneumonia. Two patients exhibited intermittent neutropenia as well. Each child had been receiving relatively high doses of corticosteroids for at least 2 months, and two were having prednisone tapered when pneumonia developed. One child responded to trimethoprim/sulfamethoxazole and pentamidine, but the other two patients died. Infants with Diamond-Blackfan anemia receiving prolonged corticosteroid therapy should receive P. carinii pneumonia prophylaxis, such as trimethoprim/sulfamethoxazole, and prophylaxis should continue during corticosteroid tapering.

publication date

  • July 25, 2002

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1097/00043426-200206000-00018

PubMed ID

  • 12142794

Additional Document Info

start page

  • 410

end page

  • 2

volume

  • 24

number

  • 5