Identification of a chromosome 11q23.2-q24 locus for familial aortic aneurysm disease, a genetically heterogeneous disorder Academic Article uri icon

Overview

MeSH Major

  • Aortic Aneurysm
  • Chromosomes, Human, Pair 11

abstract

  • FAA disease is genetically heterogeneous. We have identified a novel FAA locus at chromosome 11q23.3-q24, a critical step toward elucidating 1 gene defect responsible for aortic dilatation. Future characterization of the FAA1 gene will enhance our ability to achieve presymptomatic diagnosis of aortic aneurysms and will define molecular mechanisms to target therapeutics.

publication date

  • May 22, 2001

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11369687

Additional Document Info

start page

  • 2469

end page

  • 75

volume

  • 103

number

  • 20