A randomized, double-blind, placebo-controlled trial of psychostimulants for the treatment of fatigue in ambulatory patients with human immunodeficiency virus disease Academic Article uri icon

Overview

MeSH Major

  • Central Nervous System Stimulants
  • Fatigue
  • HIV Infections
  • Methylphenidate
  • Pemoline

abstract

  • Many patients with HIV- and acquired immunodeficiency syndrome-unrelated fatigue respond favorably to treatment with methylphenidate or pemoline. Both psychostimulants appear to be equally effective and significantly superior to placebo in decreasing fatigue severity with minimal side effects. Moreover, improvement of fatigue was significantly associated with improved quality of life and decreased levels of depression and psychological distress.

publication date

  • February 12, 2001

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11176767

Additional Document Info

start page

  • 411

end page

  • 20

volume

  • 161

number

  • 3