LY294002-geldanamycin heterodimers as selective inhibitors of the PI3K and PI3K-related family Academic Article Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • HSP90 Heat-Shock Proteins
  • Neoplasms
  • Proto-Oncogene Proteins

abstract

  • Several LY294002-GM heterodimers were synthesized with the intent of modulating their activity in the presence of hsp90 and thereby creating selective inhibitors of PI3K and PI3K-related family.

publication date

  • April 9, 2001

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0960-894X(01)00099-3

PubMed ID

  • 11294389

Additional Document Info

start page

  • 909

end page

  • 13

volume

  • 11

number

  • 7