Preoperative plasma levels of transforming growth factor beta1 (TGF-β1 strongly predict progression in patients undergoing radical prostatectomy Academic Article uri icon

Overview

MeSH Major

  • Biomarkers, Tumor
  • Prostatectomy
  • Prostatic Neoplasms
  • Transforming Growth Factor beta

abstract

  • Plasma TGF-beta(1) levels are markedly elevated in men with prostate cancer metastatic to regional lymph nodes and bone. In men without clinical or pathologic evidence of metastases, the preoperative plasma TGF-beta(1) level is a strong predictor of biochemical progression after surgery, presumably because of an association with occult metastatic disease present at the time of radical prostatectomy.

publication date

  • June 2001

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11387358

Additional Document Info

start page

  • 2856

end page

  • 64

volume

  • 19

number

  • 11