Metastatic renal cell carcinoma neovasculature expresses prostate-specific membrane antigen. Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Renal Cell
  • Endothelium, Vascular
  • Kidney Neoplasms
  • Prostate-Specific Antigen

abstract

  • As in primary prostatic adenocarcinomas, the neovasculature of metastatic prostate cancer, regardless of site, rarely express PSMA. The neovascular endothelial cells of metastatic clear cell renal carcinoma, however, express PSMA. This expression may make PSMA an effective target for mAb-based antineovasculature therapy in metastatic renal carcinoma.

publication date

  • April 2001

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11306418

Additional Document Info

start page

  • 801

end page

  • 5

volume

  • 57

number

  • 4