G-CSF induces elevation of circulating CA 15-3 in breast carcinoma patients treated in an adjuvant setting Academic Article Article uri icon

Overview

MeSH Major

  • Biomarkers, Tumor
  • Breast Neoplasms
  • Neoplasm Metastasis
  • Neoplastic Cells, Circulating

abstract

  • These data provide strong evidence that G-CSF administration can induce elevation of CA 15-3 and indicate that false-positive results should be considered when evaluating CA 15-3 in patients who are receiving G-CSF. It is speculated that this phenomenon occurs through the induction of MUC1 antigen of unknown origin by G-CSF. Experimental investigation of this clinical observation is warranted.

publication date

  • March 2001

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1002/1097-0142(20010301)91:5<909::AID-CNCR1080>3.0.CO;2-X

PubMed ID

  • 11251942

Additional Document Info

start page

  • 909

end page

  • 17

volume

  • 91

number

  • 5