Personality disorder symptoms predict declines in global functioning and quality of life in elderly depressed patients Academic Article uri icon


MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Breast Neoplasms
  • Chemotherapy, Adjuvant


  • The authors evaluated personality disorder symptoms as predictors of change in global functioning and quality of life among elderly depressed patients. Treated elderly patients (N=40) who no longer met RDC criteria for major depression were assessed for personality disorders, depression, global functioning, and quality of life after treatment of the acute episode and at 1-year follow-up. In interaction with persisting or recurrent depression, Cluster B personality disorder symptoms contributed to declines in global functioning and quality of life over a 1-year period. Personality disorder symptoms in elderly patients appear to operate as co-factors that amplify or exacerbate the impact of residual depression on long-term functioning and quality of life.

publication date

  • January 2001



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1097/00019442-200102000-00010

Additional Document Info

start page

  • 67

end page

  • 71


  • 9


  • 1