Mechanisms of prostatic stromal invasion in patients with bladder cancer: Clinical significance
Carcinoma, Transitional Cell
Urinary Bladder Neoplasms
Longitudinal sectioning of the bladder neck and prostate of cystectomy specimens suggests tumors at the bladder neck may directly invade the prostatic stroma without histological evidence of extravesical or intraurethral spread. Such direct silent tumor invasion of the prostate by superficial or endoscopically inapparent tumor is difficult to detect clinically by current biopsy methods. New methods of detection are necessary.