Sclerosing inflammatory pseudotumor of the eye. Academic Article uri icon

Overview

MeSH

  • Adult
  • Eye Enucleation
  • Histiocytes
  • Humans
  • Immunosuppressive Agents
  • Keratitis
  • Lymphocytes
  • Male
  • Neutrophils
  • Retinal Detachment
  • Scleritis
  • Sclerosis
  • Uveitis
  • Visual Acuity

MeSH Major

  • Eye Diseases
  • Granuloma, Plasma Cell
  • Sclera
  • Vitreous Body

abstract

  • We report the clinical course and pathologic findings in a case of intraocular sclerosing inflammatory pseudotumor in a 21-year-old man. The patient initially had a unilateral right interstitial keratitis, scleritis, uveitis, ciliary body mass, and retinal detachment. Scleral and vitreous biopsy specimens revealed an inflammatory process. The eye was eventually enucleated despite therapy with high doses of prednisone and ciprofloxacin hydrochloride. Histologic examination of the globe showed nongranulomatous, acute (neutrophils) and chronic (lymphocytes and histiocytes) inflammation with proliferation of fibrous tissue within the vitreous cavity, uvea, sclera, and contiguous orbital fibroadipose tissue. The contralateral eye later developed a similar mass that resolved following aggressive and prolonged immunosuppressive therapy with retention of 20/16 visual acuity.

publication date

  • April 2001

has subject area

  • Adult
  • Eye Diseases
  • Eye Enucleation
  • Granuloma, Plasma Cell
  • Histiocytes
  • Humans
  • Immunosuppressive Agents
  • Keratitis
  • Lymphocytes
  • Male
  • Neutrophils
  • Retinal Detachment
  • Sclera
  • Scleritis
  • Sclerosis
  • Uveitis
  • Visual Acuity
  • Vitreous Body

Research

keywords

  • Case Reports
  • Journal Article

Identity

Language

  • eng

PubMed ID

  • 11296029

Additional Document Info

start page

  • 603

end page

  • 607

volume

  • 119

number

  • 4