Depression and disability in late life: Directions for future research Academic Article Article uri icon


MeSH Major

  • Depressive Disorder
  • Models, Theoretical


  • The author reviews evidence from epidemiologic and clinical studies suggesting a reciprocal, potentially spiraling, relationship between depression and disability in older adults. The discussion outlines possible methodological and conceptual explanations for this evidence and poses avenues for future research. An underlying theme is the impact of how disability and depression are measured on the nature of empirical evidence and its interpretation. Measures and corresponding analytic strategies that capture the complexity of depression, disability, and their relationship are expected to lead to the most fruitful approaches to reducing the burden of depression and disability in the lives of older adults.

publication date

  • January 2001



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1097/00019442-200105000-00003

PubMed ID

  • 11316615

Additional Document Info

start page

  • 102

end page

  • 12


  • 9


  • 2