Augmentation of endothelial function by endothelin antagonism in human saphenous vein conduits Academic Article uri icon

Overview

MeSH Major

  • Antihypertensive Agents
  • Endothelin-1
  • Endothelium, Vascular
  • Oligopeptides
  • Peptides, Cyclic
  • Piperidines
  • Sulfonamides
  • Vasodilation

abstract

  • Blockade of ET receptors significantly improves endothelial function in SVs. Furthermore, these effects appear to be independently and maximally mediated by antagonism of either ET(A) or ET(B) receptors. Interventions aimed at improving endothelial function may serve to counter perioperative vasospasm and impede atherosclerosis in SVs used for revascularization procedures.

publication date

  • September 11, 2001

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11213966

Additional Document Info

start page

  • 281

end page

  • 6

volume

  • 94

number

  • 2