Cyclic immune thrombocytopenia responsive to thrombopoietic growth factor therapy Academic Article uri icon

Overview

MeSH Major

  • Polyethylene Glycols
  • Purpura, Thrombocytopenic, Idiopathic
  • Recombinant Proteins
  • Thrombocytopenia
  • Thrombopoietin

abstract

  • We report a patient with cyclic thrombocytopenia and antiplatelet antibodies, a variant of chronic immune thrombocytopenic purpura (ITP), with a several year history of periodic fluctuation of the platelet count, megakaryocytic hyperplasia and high-titer anti-GPIb-specific antiplatelet antibodies. The patient was resistant to multiple forms of therapy but has responded to the thrombopoietic growth factor, pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF). This case suggests that some patients with classic ITP may respond to thrombopoietic growth factors.

publication date

  • October 31, 2001

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/ajh.1181

PubMed ID

  • 11754405

Additional Document Info

start page

  • 210

end page

  • 4

volume

  • 68

number

  • 3