Expression of thyroid transcription factor-1 and other markers in sclerosing hemangioma of the lung Academic Article uri icon

Overview

MeSH Major

  • Biomarkers, Tumor
  • Hemangioma
  • Lung Neoplasms
  • Nuclear Proteins
  • Transcription Factors

abstract

  • The uniform positivity for EMA is consistent with the notion that the tumor cells of sclerosing hemangioma are epithelial, and the strong thyroid transcription factor-1 positivity suggests differentiation toward pulmonary epithelium. The papillary lining cells expressing EMA as well as PE10 or CAM 5.2 likely represent entrapped metaplastic alveolar epithelium, whereas the papillary lining cells expressing only EMA more likely constitute true neoplastic cells similar to those in the solid areas.

publication date

  • October 29, 2001

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11570910

Additional Document Info

start page

  • 1335

end page

  • 9

volume

  • 125

number

  • 10