Elevated expression of cyclooxygenase-2 contributes to immune dysfunction in a murine model of trauma Academic Article uri icon

Overview

MeSH Major

  • Isoenzymes
  • Prostaglandin-Endoperoxide Synthases
  • Wounds and Injuries

abstract

  • These experiments link trauma-induced increases in Cox-2 expression and PGE2 production to reduced immune function. Cox-2 represents a potential pharmacologic target to prevent or reverse trauma-induced immunosuppression.

publication date

  • November 12, 2001

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1067/msy.2001.116669

PubMed ID

  • 11685192

Additional Document Info

start page

  • 826

end page

  • 33

volume

  • 130

number

  • 5