Apoptosis and proliferation as predictors of chemotherapy response in patients with breast carcinoma
Academic ArticleArticle
Overview
MeSH Major
Breast Neoplasms
Gene Transfer Techniques
Genetic Therapy
abstract
The results of this preliminary study support evidence that chemotherapy may increase apoptosis, decrease Ki-67, and increase Bcl-2 expression in primary breast carcinomas that subsequently respond to therapy. Methodology allowing morphological confirmation of apoptosis would be advantageous.