Review article: The role of non-acid reflux in gastro-oesophageal reflux disease Review uri icon

Overview

MeSH Major

  • Gastroesophageal Reflux

abstract

  • The role of acid in the pathogenesis of gastro-oesophageal reflux disease (GERD) has been extensively studied and is well accepted. The role, if any, of non-acid reflux, in particular duodenogastro-oesophageal reflux, is much debated. The availability of new technology to detect non-acid reflux has heightened interest in this question. This article reviews the following: How do we define non-acid reflux? Does duodenogastro-oesophageal reflux (alone or in combination) cause oesophageal injury, symptoms or both? What is its role in complicated GERD? What methods are available to assess non-acid reflux? Does non-acid reflux need treatment and if so what modalities are available?

publication date

  • December 2000

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1046/j.1365-2036.2000.00875.x

PubMed ID

  • 11121901

Additional Document Info

start page

  • 1539

end page

  • 51

volume

  • 14

number

  • 12