Failure of pentavalent antimony in visceral leishmaniasis in India: Report from the center of the Indian epidemic Academic Article uri icon

Overview

MeSH Major

  • Antimony Sodium Gluconate
  • Antiprotozoal Agents
  • Disease Outbreaks
  • Leishmaniasis, Visceral

abstract

  • In India, 320 patients with visceral leishmaniasis (209 in the state of Bihar and 11 in the neighboring state of Uttar Pradesh) received identical pentavalent antimony (Sb) treatment. Sb induced long-term cure in 35% (95% confidence interval [CI], 28%-42%) of those in Bihar versus 86% (95% CI, 79%-93%) of those in Uttar Pradesh. In Bihar, the center of the Indian epidemic, traditional Sb treatment should be abandoned.

publication date

  • December 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1086/318121

PubMed ID

  • 11049798

Additional Document Info

start page

  • 1104

end page

  • 7

volume

  • 31

number

  • 4