Short-course of oral miltefosine for treatment of visceral leishmaniasis Academic Article uri icon

Overview

MeSH Major

  • Antiprotozoal Agents
  • Leishmaniasis, Visceral
  • Phosphorylcholine

abstract

  • A total of 54 Indian patients with visceral leishmaniasis were treated with oral miltefosine, 50 mg given twice daily, for 14 days (18 patients; group A), 21 days (18; group B), or 28 days (18; group C). Cure was achieved in 89% of group A, 100% of group B, and 100% of group C. Adverse reactions were self-limited and primarily mild. The 21-day miltefosine regimen combines high-level efficacy, convenient dosing, and a relatively short duration.

publication date

  • December 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1086/318122

PubMed ID

  • 11049800

Additional Document Info

start page

  • 1110

end page

  • 3

volume

  • 31

number

  • 4