Ureaplasma urealyticum colonization in the vaginal introitus and cervix of human immunodeficiency virus-infected women Academic Article uri icon


MeSH Major

  • Cervix Uteri
  • HIV Infections
  • HIV-1
  • Ureaplasma Infections
  • Ureaplasma urealyticum
  • Vagina


  • Ureaplasma urealyticum colonization was examined in paired cervical and introital specimens from 56 untreated HIV-seropositive women. Specimens were tested for U. urealyticum by polymerase chain reaction (PCR). Peripheral blood was examined for CD4 lymphocyte counts and HIV RNA concentration. U. urealyticum was detected in the cervix of 38 (69.1%) women. Introital U. urealyticum was present in 16 (28.6%) women, all of whom were cervical-positive. Cervical motion pain was present in 40.0% of women with U. urealyticum in the introitus and cervix, 23.8% of those with only cervical U. urealyticum and 5.9% of women negative for this organism (P=0.03). There was no relation between U. urealyticum colonization and CD4 lymphocyte count. However, 64.3% of women with introital U. urealyticum had circulating HIV RNA levels > 10,000 copies per ml as compared with 28.6% of women with only cervical U. urealyticum and 7.1% of women negative for this organism (P < 0.01).

publication date

  • March 16, 2000



  • Academic Article



  • eng

Digital Object Identifier (DOI)

  • 10.1258/0956462001915642

PubMed ID

  • 10726942

Additional Document Info

start page

  • 176

end page

  • 9


  • 11


  • 3