Stereotaxic injection of IgG from patients with Alzheimer disease initiates injury of cholinergic neurons of the basal forebrain
Academic Article
Overview
MeSH Major
Alzheimer Disease
Cholinergic Fibers
Immunoglobulin G
Prosencephalon
abstract
Data document that IgG from patients with AD can target a stereotaxically induced immune/inflammatory injury to cholinergic neurons in the rat basal forebrain in vivo.
