Sequential dose-intensive paclitaxel, ifosfamide, carboplatin, and etoposide salvage therapy for germ cell tumor patients Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Germinoma
  • Salvage Therapy

abstract

  • Dose-intense therapy with sequential, accelerated chemotherapy of paclitaxel/ifosfamide and carboplatin/etoposide administered with PBSC support was relatively well tolerated. The durable complete response proportion was substantial in patients with unfavorable prognostic features for achieving durable complete response to conventional-dose salvage programs. Optimal dosing of carboplatin in the high-dose setting warrants further investigation.

publication date

  • March 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10715285

Additional Document Info

start page

  • 1173

end page

  • 80

volume

  • 18

number

  • 6