Clinico-pathological features of postural hypotension in diabetic autonomic neuropathy Academic Article Article uri icon

Overview

MeSH Major

  • Cornea
  • Diabetes Mellitus, Type 1
  • Diabetes Mellitus, Type 2
  • Diabetic Neuropathies
  • Microscopy, Confocal

abstract

  • We report the clinico-pathological features and management of a 49-year-old male with a 30-year history of Type 1 diabetes mellitus who had nephropathy (proteinuria 1.81 g/24 h, creatinine 136 micromol/l), proliferative retinopathy and severe somatic and autonomic neuropathy. A sural nerve biopsy demonstrated marked myelinated fibre loss with unmyelinated fibre degeneration and regeneration combined with extensive endoneurial microangiopathy. The management of the patient's blood pressure problems (supine hypertension) and symptomatic postural hypotension is discussed.

publication date

  • March 30, 2000

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1046/j.1464-5491.2000.00238.x

PubMed ID

  • 10746489

Additional Document Info

start page

  • 163

end page

  • 6

volume

  • 17

number

  • 2