Local infusion of heparin reduces anastomotic neointimal hyperplasia in aortoiliac expanded polytetrafluoroethylene bypass grafts in baboons Academic Article uri icon

Overview

MeSH Major

  • Aorta, Abdominal
  • Blood Vessel Prosthesis
  • Fibrinolytic Agents
  • Heparin
  • Iliac Artery
  • Infusion Pumps, Implantable
  • Polytetrafluoroethylene
  • Postoperative Complications

abstract

  • These results show that local infusion of heparin significantly reduces distal anastomotic neointimal hyperplasia and cell proliferation without measurable systemic anticoagulation or other side effects. Thus, this approach may represent an attractive strategy for prolonging ePTFE bypass graft patency.

publication date

  • February 28, 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10664503

Additional Document Info

start page

  • 354

end page

  • 63

volume

  • 31

number

  • 2