Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121 Article Conference Paper uri icon

Overview

MeSH Major

  • Angioplasty, Balloon, Coronary
  • Coronary Artery Bypass
  • Coronary Disease
  • Stents

abstract

  • These studies demonstrate that direct intramyocardial administration of Ad(GV)VEGF121.10 results in focal genome and VEGF levels, including focal angiogenesis, sufficient to normalize blood flow to the ischemic myocardium, findings that are relevant to designing human trials of gene therapy-mediated cardiac angiogenesis.

publication date

  • January 2000

Research

keywords

  • Conference Paper

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0003-4975(99)01102-9

PubMed ID

  • 10654479

Additional Document Info

start page

  • 14

end page

  • 23; discussion 23-4

volume

  • 69

number

  • 1