Histamine and tryptase levels in patients with acute allergic reactions: An emergency department-based study Academic Article uri icon

Overview

MeSH Major

  • Emergency Medical Services
  • Histamine
  • Hypersensitivity, Immediate
  • Serine Endopeptidases

abstract

  • Raised histamine and, less commonly, raised tryptase levels are observed in almost 50% of patients presenting to emergency departments with acute allergic reactions. Some cases associated with systemic mediator release do not have classical features of severe anaphylaxis, such as hypotension or tachycardia. The lack of total tryptase elevations in many patients with elevated plasma histamine levels suggests basophil involvement. The clinical utility of beta-tryptase determinations in the evaluation of acute allergic reactions needs further study.

publication date

  • July 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1067/mai.2000.107600

PubMed ID

  • 10887307

Additional Document Info

start page

  • 65

end page

  • 71

volume

  • 106

number

  • 1 I