Lung redox homeostasis: emerging concepts. Review uri icon

Overview

MeSH

  • Animals
  • Endothelium, Vascular
  • Oxidation-Reduction
  • Oxidative Stress
  • Pulmonary Circulation

MeSH Major

  • Homeostasis
  • Lung

abstract

  • This symposium was organized to present some aspects of current research pertaining to lung redox function. Focuses of the symposium were on roles of pulmonary endothelial NADPH oxidase, xanthine oxidase (XO)/xanthine dehydrogenase (XDH), heme oxygenase (HO), transplasma membrane electron transport (TPMET), and the zinc binding protein metallothionein (MT) in the propagation and/or protection of the lung or other organs from oxidative injury. The presentations were chosen to reflect the roles of both intracellular (metallothionein, XO/XDH, and HO) and plasma membrane (NADPH oxidase, XO/XDH, and unidentified TPMET) redox proteins in these processes. Although the lung endothelium was the predominant cell type under consideration, at least some of the proposed mechanisms operate in or affect other cell types and organs as well.

publication date

  • September 2000

has subject area

  • Animals
  • Endothelium, Vascular
  • Homeostasis
  • Lung
  • Oxidation-Reduction
  • Oxidative Stress
  • Pulmonary Circulation

Research

keywords

  • Journal Article
  • Review

Identity

Language

  • eng

PubMed ID

  • 10956613

Additional Document Info

start page

  • L413

end page

  • L417

volume

  • 279

number

  • 3