An endogenous inhibitor of nitric oxide synthase regulates endothelial adhesiveness for monocytes Academic Article Article uri icon

Overview

MeSH Major

  • Education, Medical
  • Education, Medical, Continuing
  • Specialization
  • Vascular Diseases

abstract

  • We concluded that the endogenous NO synthase inhibitor ADMA is synthesized in human endothelial cells. Asymmetric dimethylarginine increases endothelial oxidative stress and potentiates monocyte binding. Asymmetric dimethylarginine may be an endogenous proatherogenic molecule.

publication date

  • December 14, 2000

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0735-1097(00)01013-5

PubMed ID

  • 11127475

Additional Document Info

start page

  • 2287

end page

  • 95

volume

  • 36

number

  • 7