A modified transorbital baboon model of reperfused stroke Academic Article uri icon

Overview

MeSH Major

  • Brain
  • Cerebral Infarction
  • Disease Models, Animal
  • Papio
  • Stroke

abstract

  • Transorbital temporary occlusion of the entire anterior cerebral circulation with strict control of physiological parameters can reliably produce reperfused MCA territory infarction. The magnitude of the resultant infarct with little interanimal variability diminishes the potential number of animals required to distinguish between 2 treatment regimens. The anatomic distribution of the infarct and associated functional deficits offer comparability to human hemispheric strokes.

publication date

  • December 14, 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11108772

Additional Document Info

start page

  • 3054

end page

  • 63

volume

  • 31

number

  • 12