Dendritic cells armed with anti-CD3 mAbs reduce pulmonary metastases, prolong survival, and engender antitumor effector cells demonstrable by adoptive transfer Academic Article uri icon

Overview

MeSH Major

  • Antigens, CD3
  • Carcinoma, Renal Cell
  • Dendritic Cells
  • Immunotherapy, Adoptive
  • Lung Neoplasms

abstract

  • Our data suggest that the therapeutic efficacy of DCs pulsed with tumor cells can be augmented by arming them with anti-CD3 mAbs. DC-based treatment regimens that currently are being pursued in clinical trials might be improved by equipping such cells with anti-CD3 mAbs.

publication date

  • December 27, 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 11129426

Additional Document Info

start page

  • 771

end page

  • 6

volume

  • 7

number

  • 10