Pharmacokinetics of 111In- and 125I-labeled antiTac single-chain Fv recombinant immunotoxin Academic Article uri icon

Overview

MeSH Major

  • Immunotoxins
  • Indium Radioisotopes
  • Iodine Radioisotopes

abstract

  • We evaluated the biodistribution, pharmacokinetics, and catabolism of 111In-labeled antiTac(Fv)-PE38 and found that it differed from 125I-labeled antiTac(Fv)PE38. These studies suggest that 111In-labeled antiTac(Fv)-PE38 can be used to trace the fate of antiTac(Fv)-PE38 in humans.

publication date

  • April 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10768579

Additional Document Info

start page

  • 755

end page

  • 62

volume

  • 41

number

  • 4