Binding of [99mTc]TRODAT-1 to dopamine transporters in patients with Parkinson's disease and in healthy volunteers Academic Article uri icon

Overview

MeSH Major

  • Brain
  • Carrier Proteins
  • Membrane Glycoproteins
  • Membrane Transport Proteins
  • Nerve Tissue Proteins
  • Organotechnetium Compounds
  • Parkinson Disease
  • Tropanes

abstract

  • The findings indicate that Parkinson's disease can be detected with [99mTc]TRODAT by simply inspecting the images for uptake in the posterior putamen. Appropriate asymmetries seem to be visible with quantification in patients with clinically defined hemi-Parkinson's disease, even though changes in the putamen contralateral to the clinically unaffected side in these patients appear to precede the development of symptoms.

publication date

  • April 2000

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10768556

Additional Document Info

start page

  • 584

end page

  • 9

volume

  • 41

number

  • 4