Angiogenesis gene therapy: Phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease Academic Article uri icon

Overview

MeSH Major

  • Adenoviridae
  • Coronary Circulation
  • Coronary Disease
  • Endothelial Growth Factors
  • Genetic Therapy
  • Genetic Vectors
  • Lymphokines
  • Neovascularization, Physiologic

abstract

  • The data are consistent with the concept that direct myocardial administration of Ad(GV)VEGF121.10 to individuals with clinically significant coronary artery disease appears to be well tolerated, and initiation of phase II evaluation of this therapy is warranted.

publication date

  • August 3, 1999

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10430759

Additional Document Info

start page

  • 468

end page

  • 74

volume

  • 100

number

  • 5