Sensitization to Aspergillus species in the congenital neutrophil disorders chronic granulomatous disease and hyper-IgE syndrome Academic Article uri icon

Overview

MeSH Major

  • Aspergillosis
  • Aspergillus fumigatus
  • Granulomatous Disease, Chronic
  • Job Syndrome

abstract

  • Patients with HIE syndrome and CGD have a high incidence of sensitization to Aspergillus species. A clinical picture indistinguishable from ABPA may coexist or emerge in patients with CGD or HIE and create a major management dilemma because systemic corticosteroids may accelerate tissue damage and invasive fungal infections. It is important to distinguish individuals with congenital neutrophil disorders from uncomplicated classic ABPA.

publication date

  • December 1999

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10589011

Additional Document Info

start page

  • 1265

end page

  • 72

volume

  • 104

number

  • 6