Autoantibodies to RNA polymerases recognize multiple subunits and demonstrate cross-reactivity with rna polymerase complexes
Membrane Transport Proteins
Molecular Dynamics Simulation
Anti-RNAP antibodies recognize multiple subunits of RNAP I, II, and III. Moreover, the results of this study provide the first direct evidence that antibodies that recognize shared subunits of human RNAPs or epitopes present on different human RNAP subunits are responsible for the recognition of multiple RNAPs by SSc sera.