p53 Immunolocalization in cell block preparations of squamous lesions of the neck: An adjunct to fine-needle aspiration diagnosis of malignancy
Carcinoma, Squamous Cell
Head and Neck Neoplasms
Tumor Suppressor Protein p53
Our findings suggest that p53 immunostaining is helpful in differentiating benign and malignant squamous lesions. While negative staining for p53 does not exclude malignancy, positive immunostaining may aid in accurate fine-needle aspiration diagnosis of malignancy in cytomorphologically equivocal squamous lesions of the neck.