Allogeneic bone marrow transplantation versus chemotherapy for the treatment of childhood acute lymphoblastic leukemia in second remission: A single-institution study Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Bone Marrow Transplantation
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma

abstract

  • In our single-institution series, unmodified HLA-matched allogeneic sibling transplants using hyperfractionated TBI and cyclophosphamide for patients with ALL in CR2 have resulted in superior outcome with a significantly improved probability of DFS and a lower relapse rate, as compared with those for patients treated with chemotherapy, regardless of the duration of first remission, the disease characteristics at diagnosis, or the intensity of prior treatment during first remission.

publication date

  • January 1999

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10458234

Additional Document Info

start page

  • 197

end page

  • 207

volume

  • 17

number

  • 1