Acquired factor VIII inhibitors - Successful treatment with an oral outpatient regimen Academic Article uri icon

Overview

MeSH Major

  • Factor VIII

abstract

  • A rare cause of a spontaneous, life threatening coagulopathy in adults is the development of autoantibodies to factor VIII. We recently had the opportunity to treat seven patients with this disorder. After stabilization, they were given a regimen consisting of prednisone and oral cyclophosphamide. All patients had a complete response to treatment. The median time to response was three weeks. Durable remissions were achieved, making this oral regimen an acceptable treatment for this disorder.

publication date

  • December 1999

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 9883809

Additional Document Info

start page

  • 70

end page

  • 1

volume

  • 60

number

  • 1