Phase II trial of weekly irinotecan plus cisplatin in advanced esophageal cancer Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Antineoplastic Combined Chemotherapy Protocols
  • Carcinoma, Squamous Cell
  • Esophageal Neoplasms

abstract

  • The combination of weekly cisplatin plus irinotecan had significant activity in metastatic esophageal carcinoma and resulted in significant relief of dysphagia. The regimen was well tolerated, with acceptable myelosuppression and rare treatment-related diarrhea. Further evaluation of the combination of weekly irinotecan and cisplatin, including the addition of other agents to this regimen, is indicated.

publication date

  • October 1999

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10506629

Additional Document Info

start page

  • 3270

end page

  • 5

volume

  • 17

number

  • 10