Therapeutic efficacy of an anti-IL-5 monoclonal antibody delivered into the respiratory tract in a murine model of asthma Academic Article Article uri icon

Overview

MeSH Major

  • Alveolitis, Extrinsic Allergic

abstract

  • This is the first study to demonstrate that delivery of anti-IL-5 mAbs into the respiratory tract is efficacious in attenuating the asthma phenotype in a murine model. These results provide impetus for the development of inhaled IL-5 antagonists for the treatment of human asthma.

publication date

  • August 12, 1999

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0091-6749(99)70138-7

PubMed ID

  • 10400864

Additional Document Info

start page

  • 215

end page

  • 21

volume

  • 104

number

  • 1