Open trial of flutamide for treatment of obsessive-compulsive disorder Academic Article uri icon

Overview

MeSH Major

  • Androgen Antagonists
  • Flutamide
  • Obsessive-Compulsive Disorder

abstract

  • The lack of response to treatment with flutamide, an androgen receptor antagonist, suggests that any effects of gonadal steroids to exacerbate OCD symptoms are more likely to be mediated through estrogen receptors or through mechanisms that do not involve classical intracellular androgen receptors. Future treatment trials should examine agents that antagonize estrogen receptors or otherwise inhibit estrogen activity.

publication date

  • July 1999

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10453797

Additional Document Info

start page

  • 442

end page

  • 5

volume

  • 60

number

  • 7