Local L-arginine delivery after balloon angioplasty reduces monocyte binding and induces apoptosis Academic Article uri icon

Overview

MeSH Major

  • Angioplasty, Balloon
  • Apoptosis
  • Arginine
  • Endothelium, Vascular
  • Monocytes

abstract

  • Intramural delivery of L-arginine immediately after angioplasty causes a sustained increase in tissue L-arginine levels associated with enhancement of local NO synthesis. The local increase in NO synthesis is associated with an attenuation of monocyte binding and increased apoptosis of resident macrophages. This treatment strategy could be valuable for the prevention and management of restenosis.

publication date

  • October 26, 1999

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 10534472

Additional Document Info

start page

  • 1830

end page

  • 5

volume

  • 100

number

  • 17