Medical therapy: Management of the refractory patient Review uri icon

Overview

MeSH Major

  • Gastroesophageal Reflux

abstract

  • Although relatively rare, GERD patients refractory to medical therapy remain a challenge for the clinician. Refractoriness can be diagnosed only if the patient is properly studied on medication and if what should be adequate medical therapy has been given a sufficient therapeutic trial. Use of 24-hour intragastric and intraesophageal pH-metry has improved the ability to manage patients who appear to be nonresponders. Simple advice and minor adjustments to medical therapy are usually all that is needed for most patients, but in some, management requires knowledge of the principles outlined in this article. If followed, only a small group of patients should be medically refractory.

publication date

  • January 1999

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/S0889-8553(05)70093-5

PubMed ID

  • 10695005

Additional Document Info

start page

  • 847

end page

  • 60

volume

  • 28

number

  • 4